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Systems Biology and Bioinformatics Laboratory
Research Projects
Our Current Focus
Bioinformatics model and pipeline development to integrate
bulk/single-cell/spatial omics data
Functional consequence of somatic mosaicism in aging and cancer
Multi-omics integration to improve clinical diagnosis and treatment
project : AI model to infer SV breakpoint from single-cell epigenome (database for scDNA-seq)
project : AI based inference of lncRNA expression from scATAC-seq
project : Detection of ecDNA from single-cells
project : Bioinformatics pipeline in BI/computing core
(참여 연구자 : 노희완 연구원)
project : Functional consequence of
SVs on 3D genome
project : Bone Marrow aging and Clonal hematopoiesis (Collaborator : Dr. Karen Grimes, Dr. Ashley Sanders, Prof. Jan Korbel, )
project : Tumor heterogeneity induced by drug (Collaborator : Prof. Jan Korbel, Maja Starostacka)
project : Tumor heterogeneity in complex karyotype AML (Collaborator : Dr. Karen Grimes, Dr. Ashley Sanders, Prof. Jan Korbel, Prof. Andreas Trummp)
project : T cell heterogeneity (Collaborator : Prof. Je-Min Choi)
(참여 연구자 : 김경민 박사과정 파견 연구원)
project : Cellular heterogeneity in liver diseases (Collaborator : Prof. Dae Won Jun)
(참여 연구자 : 이성준 석사과정 학생 연구원)
project : Multi-omics analysis of cancer drug resistance (Collaborator : Prof. Kyung-min Lee)
(참여 연구자 : 노희완 연구원)
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