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Research Projects

Our Current Focus

Cause and consequence of somatic mosaicism in aging and cancer

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project : AI-guided modeling of epigenetic determinant of genome instability

project : Single-cell Nucleosome Atlas

project : Driver pathways of clonal expansion
in cancer relapse after treatment

 

Multi-omics integration to improve clinical diagnosis and treatment

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project : T cell heterogeneity
(Collaborator : Prof. Je-Min Choi)

project : Cellular heterogeneity in liver diseases (Collaborator : Prof. Dae Won Jun)

project : Multi-omics analysis of PDAC initiation (Collaborator : Prof. Boyoun Park)


project : T cell clone expansion in disease

Bioinformatics model and pipeline development to integrate
bulk/single-cell/spatial omics data

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project : AI/ML to infer SV breakpoint from single-cell epigenome

project : AI/ML based inference of gene expression from nucleosome occupancy

project : AI-guided cell type annotation


project : Multi-omics analysis to dissect
gene regulatory network in plants

MultiOmics to link genome & epigenome

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