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Systems Biology and Bioinformatics Laboratory


Research Projects
Our Current Focus
Cause and consequence of somatic mosaicism in aging and cancer

project : AI-guided modeling of epigenetic determinant of genome instability
project : Single-cell Nucleosome Atlas
project : Driver pathways of clonal expansion
in cancer relapse after treatment
Multi-omics integration to improve clinical diagnosis and treatment

project : T cell heterogeneity
(Collaborator : Prof. Je-Min Choi)
project : Cellular heterogeneity in liver diseases (Collaborator : Prof. Dae Won Jun)
project : Multi-omics analysis of PDAC initiation (Collaborator : Prof. Boyoun Park)
project : T cell clone expansion in disease
Bioinformatics model and pipeline development to integrate
bulk/single-cell/spatial omics data

project : AI/ML to infer SV breakpoint from single-cell epigenome
project : AI/ML based inference of gene expression from nucleosome occupancy
project : AI-guided cell type annotation
project : Multi-omics analysis to dissect
gene regulatory network in plants
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