top of page
Systems Biology and Bioinformatics Laboratory
Research Projects
Our Current Focus
Bioinformatics model and pipeline development to integrate
bulk/single-cell/spatial omics data
Functional consequence of somatic mosaicism in aging and cancer
Multi-omics integration to improve clinical diagnosis and treatment
project : AI model to infer SV breakpoint from single-cell epigenome (database for scDNA-seq)
project : AI based inference of lncRNA expression from scATAC-seq
project : Detection of ecDNA from single-cells
project : Bioinformatics pipeline in
multi-omics analysis
project : Detection and exploration of
functional consequence of SVs on 3D genome
project : Bone Marrow aging and Clonal hematopoiesis (Collaborator : Dr. Karen Grimes, Dr. Ashley Sanders, Prof. Jan Korbel, )
project : Tumor heterogeneity induced by drug (Collaborator : Prof. Jan Korbel, Maja Starostacka)
project : Tumor heterogeneity in complex karyotype AML (Collaborator : Dr. Karen Grimes, Dr. Ashley Sanders, Prof. Jan Korbel, Prof. Andreas Trummp)
project : T cell heterogeneity (Collaborator : Prof. Je-Min Choi)
project : Cellular heterogeneity in liver diseases (Collaborator : Prof. Dae Won Jun)
project : Multi-omics analysis of PDAC initiation (Collaborator : Prof. Boyoun Park)
project : Dissect the functional role of novel TFs in immune system
bottom of page